Potts shunt for the treatment of suprasystemic pulmonary artery hypertension: geometric multiscale and reduced models

  • Pant, Sanjay (Swansea University)
  • Sizarov, Aleksander (Department of Pediatrics, Maastricht University Medical Centre)
  • Knepper, Angela (Swansea University)
  • Gossard, Gaetan (INRIA)
  • Noferi, Alberto (INRIA)
  • Boudjemline, Younes (Sidra Heart Center)
  • Vignon-Clementel , Irene E. (INRIA)

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The Potts shunt (PS) is an anastomosis that connects the left pulmonary artery to the descending aorta. It has been proposed as a potential palliative treatment of drug-resistant suprasystemic pulmonary arterial hypertension (PAH). We propose a geometric multiscale (GMS) model to study the changes in both local and global haemodynamics induced by the Potts shunt. GMS model parameters are estimated to reproduce the pre-operative measurements of a patient with suprasystemic idiopathic PAH, who received a PS percutaneously. Model validation is performed by comparison of model output against the post-operative measurements.